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#99087 Prion Research Associate

Extended Review Date: Mon 6/10/2019

This position will remain open until a successful candidate has been identified.

This is a limited appointment with the possibility of extension/career conversion.

Special Selection Applicants: Apply by 05/03/19. Eligible Special Selection clients should contact their Disability Counselor for assistance.


Under supervision of the PI, incumbent will conduct study of prion diseases with molecular and cellular methods, including transgenic mice. Perform a wide variety of molecular biology, biochemical, and tissue culture techniques using in vivo and in vitro model systems to aid in the study of prion pathogenesis. The incumbent will be responsible for performing techniques, including DNA cloning, preparing viral vectors, PCR, westerns, ELISAs, and immunohistochemistry. Participate in animal studies including maintaining a mouse colony. Also, responsible for inventory, ordering lab supplies, and regulatory compliance administration.


  • Theoretical knowledge of a life science such as typically acquired by a Bachelor's Degree in biochemistry, structural biology, general chemistry, cellular and/or molecular biology and/or; applicable work experience.

  • Proven ability to handle and monitor small laboratory animals. Knowledge to administer medications, euthanize small laboratory animals, collect tissues at necropsy and trim tissues for histological analysis.

  • Demonstrated ability to perform routine PCR, RT-PCR, qPCR, ELISA, and tissue culture protocols.

  • Demonstrated knowledge of protein analysis techniques: western blot.

  • Demonstrated ability to perform DNA cloning and prepare viral vectors.

  • Proven ability to accurately weigh chemical compounds, prepare accurate dilutions, calculate concentrations and prepare buffers.

  • Strong skill in accurate record keeping and ability to organize, analyze, and calculate data.

  • Knowledge of appropriate procedures and rules for handling, storing, and disposing of biohazardous, carcinogenic, and chemical materials.

  • Strong knowledge and experience in the proper use and maintenance of laboratory equipment (i.e. high speed centrifuges, pH meter, spectrophotometric equipment, electrophoresis, PCR apparatus, etc.).

  • Demonstrated experience in regulatory compliance authorizations and administration.

  • Proficient computer skills including experience with word processing, spreadsheet, data management, presentation, and internet-based software.


Experience writing IACUC and IRB protocols or sections.


  • Employment is subject to a criminal background check.
  • Willing to work with hazardous materials (biological, chemical, and radioactive) and animals.
  • Ability to work overtime and weekends as experimental protocols demand.

UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!


Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.


UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html

UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.

UC San Diego School of Medicine
Payroll Title:
Salary Range
Commensurate with Experience
Appointment Type:
Limited Appointment
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Days, 8 hrs/day, Monday-Friday


As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.