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#108978 Mouse Colony Manager/Research Associate

Extended Review Date: Mon 6/7/2021

This position will remain open until a successful candidate has been identified.

UCSD Layoff from Career Appointment: Apply by 04/28/21 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 05/07/21. Eligible Special Selection clients should contact their Disability Counselor for assistance.


The UCSD Department of Cellular and Molecular Medicine (CMM) is one of two basic science units in the School of Medicine where world-class researchers study fundamental cellular processes and pathways using a variety of techniques from classical genetics and fluorescence microscopy to high-throughput genomics, systems biology, and crystallography. Our 36 faculty and over 200 postdoctoral scholars, graduate students, and research staff work on the cutting edge of biology, cutting across fields from basic biochemistry and genetics to genomics, systems biology and stem cell biology. The faculty also play a major role in medical and graduate student training, providing educational and programmatic offerings that span several disciplines and provide diversity to meet the interests of a broad spectrum of students and scholars. We constantly seek to recruit highly motivated, technologically-advanced, and deeply interested individuals who are ready to become a part of our dynamic research and educational environment.

Incumbent will work in a lab, whose members have diverse backgrounds, encompassing computer science, materials science, engineering, RNA biology, neurobiology, biochemistry, and therapeutic development. The majority of lab members use a combination of tissue-culture based and animal models and high-throughput genomics methodologies, to gain insight into RNA mediated cellular processes in health and disease.

To support our animal studies, we seek a motivated, diligent and highly organized individual to support our animal modeling studies. Incumbent work with lab trainees and staff to perform mouse injections, surgeries, tissue dissections, and immunohistochemistry procedures. Incumbent will also oversee mouse colony management, assist Animal Care Program staff in colony maintenance and animal care procedures. Previous experience in two or more of the following areas is essential: (1) mouse colony management, (2) animal surgery, (3) tissue processing and immunohistochemistry; (4) confocal microscopy.


  • Theoretical and/or practical knowledge in cellular and molecular biology, immunology, or related field as typically attained by a Bachelor's degree, or an equivalent combination of education and experience.

  • Demonstrated experience with immunohistochemistry and/or confocal microscopy.

  • Experience with all aspects of mouse colony management including mouse genotyping, husbandry methods, breeding, weaning, tail clipping of offspring, surgical procedures and injections, tissue processing and maintenance of water system, cage and water bottles.

  • Ability to maintain effective working relationships with other staff members, students, faculty and scientists. Ability to exercise judgement, initiative and resourcefulness in making decisions under supervision.

  • Excellent communication skills to interact with faculty, staff, and students as well as appropriate campus department personnel. Skill and knowledge to collaborate with colleagues.

  • Demonstrated ability to manage a complex work schedule.

  • Experience with general lab maintenance including cleaning, stocking supplies.

  • Experience with UCSD Animal Subjects procedures.

  • Ability to maintain accurate data records from detailed observation of experimentation, and to transcribe precise, cogent results for possible scientific journal publication.

  • Proven experience performing molecular biology techniques including PCR, DNA preparation/extraction, gel electrophoresis and Southern Blot.

  • Experience in performing biochemistry and laboratory techniques and demonstrated experience to prepare buffers and solutions, as well as various staining solutions.

  • Experience in clinical and/or research technical procedures, such as the developmental and production of transgenic mice, breeding colony management, blood and tissue collection. Experience and theoretical knowledge of normal physiological data of rodents, particularly mice, and skill in the recognition of abnormal behavior and health.

  • Strong experience in operating bioclean environmental room and understanding the concept of sterility and transfer of pathogens.

  • Proficient knowledge and experience using Microsoft Word, Excel and gMouse (mouse management software).


  • Familiarity with University/NIH/AALAC policies and compliance procedures.
  • Experience with UCSD EH&S regulations and laboratory safety procedures including radioactive waste management and disposal.
  • Experience working with Macintosh OSX.


  • Employment is subject to a criminal background check.
  • Must be willing to work flexible schedule in order to complete experiments as necessary.
  • Occasional evenings and weekends may be required.
  • Must be willing to work with mice and perform minor mouse surgeries and tissue dissections.
  • No allergies to animals.
  • Must be willing to work in close proximity to hazardous materials.

UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!


Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.


UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html

UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.

UC San Diego School of Medicine
Payroll Title:
Salary Range
Commensurate with Experience
La Jolla
Appointment Type:
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Days, 8 hrs/day, Monday - Friday


As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.