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#103008 Staff Research Associate III

Filing Deadline: Wed 3/4/2020

UCSD Layoff from Career Appointment: Apply by 12/16/19 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 12/26/19. Eligible Special Selection clients should contact their Disability Counselor for assistance.


The multi-disciplinary laboratory within the Department of Pediatrics works in the fields of RNA and Chemical biology. The laboratory explores the role of RNA modifications in cancer, immunity, and stem cell biology. Projects in the lab use cell culture, animal models, neural stem cells, 3D organoids, human pluripotent cells and several molecular tools to investigate fundamental mechanisms of cancer development, AIDS, and immune disorders.

Under general supervision of the Principal Investigator, the Staff Research Associate (SRA) III will perform cellular lab experiments, making significant independent contributions in the design, troubleshooting, modification and analysis of experiments and protocols. Incumbent will also perform experiments using tissue culture techniques such as PCR, plasmid purification, iPSC production and characterization, and HT screening and sequencing, gene silencing, cloning, CRISPR genome editing, cancer models, drug treatments, under general supervision. In addition, the incumbent will independently support duties to include RT-PCR, qPCR, DNA and RNA molecular experiments, western blotting, immunoprecipitation, affinity purification, analyze and report data, prepare complex solutions, reagents and culture media and run cell analyses to ensure quality and control.

The SRA will be responsible for implementing and performing a variety of new and on-going experimental protocols, making significant research contributions to the laboratory and making innovative contributions pertaining to complex experimental procedures of iPSC production and characterization. May provide training and direction and work cooperatively with other SRAs, including doctoral and student lab assistants. Compile and analyze research data, draft articles and grant proposals.


  • Advanced theoretical knowledge of and direct experience with Stem Cell biology as typically attained by a Bachelor's Degree; or an equivalent combination of education and experience.

  • Strong experience with research design, protocol development, and qualitative and quantitative research methods to independently address scientific challenges to move the project forward.

  • Proven experience authoring journal articles, abstracts, and posters. Ability to prepare papers for publication and research proposals. Ability to read, comprehend and discuss research materials. Review the scientific articles and make innovative contributions to develop new research techniques and improve current protocols for the research projects.

  • Demonstrated knowledge of microscopy imaging procedures and in vivo analysis.

  • Strong demonstrated experience in qualitative research methods.

  • Demonstrated ability to perform scientific procedures including confocal microscopy, DNA and RNA isolation, and histological analysis.

  • Advanced knowledge and experience working with and handling small animals including mice. Knowledge of normal physiological data of rodents, particularly mice. Experience with small animal husbandry and excellent organizational skills to manage all lab animal work.

  • Proven knowledge of laboratory safety including radioactive/biohazard handling and disposal techniques, and the ability to ensure laboratory compliance with required safety regulations.


PhD in cell biology, biochemistry, chemical biology, or genetics.


  • Employment is subject to a criminal background check.
  • Occasional evenings and weekends may be required.
  • Must have access to reliable transportation.
  • Must be willing to work with hazardous materials.
  • Must be willing to work with small animals.

UC San Diego Health is the only academic health system in the San Diego region, providing leading-edge care in patient care, biomedical research, education, and community service. Our facilities include two university hospitals, a National Cancer Institute-designated Comprehensive Cancer Center, Shiley Eye Institute, Sulpizio Cardiovascular Center, and several outpatient clinics. UC San Diego Medical Center in Hillcrest is a designated Level I Trauma Center and has the only Burn Center in the county. We invite you to join our dynamic team!


Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.


UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html

UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.

UC San Diego School of Medicine
Payroll Title:
Salary Range
Commensurate with Experience
Appointment Type:
Appointment Percent:
RX Contract
Total Openings:
Work Schedule:
Days, 8 hrs/day, Mon-Fri


As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening.